Dramatica can be used for non-fiction if you're writing something with an opinion, such as an essay or a piece of non-fiction told in a slightly novelized fashion. If your intent is to create a piece of non-fiction in which the author does not make any value judgments, then Dramatica will not be of much use. Dramatica is designed to help a writer create a compelling argument to his audience, one that has definite opinions.

Many biographies and histories are fictionalized to make them more interesting and accessible to an audience, often achieved by omitting or rearranging events. The movie "Ray" is a recent example. However, many biographies and histories are written as objective observations and recollections of events in a person's life or in a particular place at a particular time. Dramatica is great for the former, not much use for the latter.