If the Antagonist changes, will that result in a Happy Ending?

I have a wife as the Antagonist, but I want in the end for the husband and wife to come back together again. Is it possible?

Certainly. Scrooge in A Christmas Carol is certainly the Antagonist (though he happens to be the MC as opposed to the IC), and as a result of his change he is now back in the graces of his fellow Londoners, including his nephew, his debtors, and Bob Cratchet and family.

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